Horizon Interdisciplinary Journal 2024-05-21T19:44:11+00:00 Dr. Efraín Armenta Rojas [email protected] Open Journal Systems <p><strong>LEGAL INFORMATION</strong></p> <p><strong>COPYRIGHT AND RELATED RIGHTS</strong></p> <p><strong>HORIZON INTERDISCIPLINARY JOURNAL</strong><span style="font-weight: 400;">, </span><strong>year 2, no. 2, April-June 2024</strong><span style="font-weight: 400;">, is a quarterly publication "January-March", "April-June", "July-September", October-December "published by the Fundación Enfermera Delia Ruíz Rivas. General Ferreira 2264, Colonia Cacho, Tijuana, B.C. Tel. 664 825 9407, web page of the journal: <a href=""></a>, and </span><a href=""><span style="font-weight: 400;">Fundación Enfermera Delia Ruíz Rivas</span></a><span style="font-weight: 400;">. Editor in Chief: Dr. Efraín Armenta Rojas, whose e-mail address is: [email protected]. Responsible for the latest update of this issue, Dr. Efraín Armenta Rojas, whose e-mail address is: [email protected], Fundación Enfermera Delia Ruíz Rivas. General Ferreira 2264, Colonia Cacho, Tijuana, B.C. Date of last modification, May 21, 2024. <strong>Right of exclusive use No. 04-2023-012317363900-102, ISSN: 2992-7706.</strong><br /></span></p> <p><span style="font-weight: 400;">The content expressed by the authors of the papers does not necessarily reflect the position of the editorial board.</span></p> <h3><strong>Focus and Scope</strong></h3> <p><span style="font-weight: 400;">The purpose of the <strong>Horizon Interdisciplinary Journal</strong></span><span style="font-weight: 400;"><strong> </strong>is to disseminate the original research and technological development carried out by the scientific community in all areas including all medical sciences and technology.</span></p> <p><span style="font-weight: 400;">7 main thematic topics are included:</span></p> <ol> <li style="font-weight: 400;" aria-level="1"><strong>Nursing: </strong>Advanced Practice Nursing, Esthetic/Cosmetic, Ambulatory Care, Burn, Camp, Cardiac, Interventional Cardiac, Diabetes, Dental, Medical Case Management, Community Health, Correctional, Critical Care, Emergency, Health environmental, faith community, flight, forensic, gastroenterology, genetics, geriatrics, hematology, health visits, holistic, home care, hospice and palliative care, hyperbaric, immunology and allergies, intravenous therapy, infection control, infectious disease, legal, maternal-child, medical-surgical, military and uniformed services, neonatal, neurosurgical, nephrology, lawyer, nursing informatics, nursing management, nursing research, obstetrics, obstetrics g, occupational health, oncology, orthopedic, ostomy, pediatric, perianesthesia, perioperative, psychiatric, private, public health, nursing pulmonary medicine, quality improvement, radiology, rehabilitation nursing, research, renal, school, space, subacute, substance abuse, surgical, telenursing, telephone triage, transplant, travel, urology, management of utilization, vascular access, wound care.</li> <li style="font-weight: 400;" aria-level="1"><strong>Medicine: </strong>Cardiology, Gastroenterology &amp; Hepatopancreatobiliary Medicine, Clinical Neurology, Oncology, Orthopedics, Endocrinology &amp; Metabolism, Nephrology &amp; Urology, Epidemiology &amp; Public Health, Stomatology, Pulmonology, Ophthalmology, Obstetrics &amp; Gynecology, Immunology, Hematology, Clinical Psychology &amp; Psychiatry, Otolaryngology, Dermatology, Clinical Pharmacology</li> <li style="font-weight: 400;" aria-level="1"><strong>Odontology: </strong>Management of dental disease, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research.</li> <li style="font-weight: 400;" aria-level="1"><strong>Psychology: </strong>Developmental, cognitive, educational, clinical, health, organizational, evolutionary, and personality psychology, the impact of social media on mental health and well-being, cognitive-behavioral therapy: theory, techniques, and applications, the psychology of resilience: factors and interventions that promote adaptive coping, psychological factors in motivation and achievement, the role of psychology in understanding and addressing stigma and discrimination.</li> <li style="font-weight: 400;" aria-level="1"><strong>Nutrition:</strong> Human milk molecules, breastfeeding, growth &amp; Development, gut microbiota, obesity, allergies, malnutrition, low birth weight.</li> <li style="font-weight: 400;" aria-level="1"><strong>Clinical Biochemistry:</strong> Diagnostic applications of biochemical markers, precision medicine in clinical biochemistry, molecular diagnostics in clinical biochemistry, biomarkers in cancer diagnosis and prognosis, role of biochemical markers in neurodegenerative disorders, pharmacogenomics, emerging technologies in clinical biochemistry, metabolomics in clinical biochemistry, oxidative stress markers, hormonal markers in endocrine disorders, biochemical markers in autoimmune diseases, biochemical assessment of nutritional status.</li> <li style="font-weight: 400;" aria-level="1"><strong>Pharmacology:</strong> pharmacokinetics and pharmacodynamics of commonly used drugs, drug interactions: Mechanisms and clinical implications, pharmacogenomics and personalized medicine in pharmacology, adverse drug reactions and their management, role of drug metabolism in therapeutic efficacy and safety, drug development and clinical trials, drug delivery systems, rational use of drugs, pharmacovigilance, pharmacotherapy of infectious diseases, pharmacology of drug abuse and addiction, pharmacotherapy for pain management, pharmacoeconomics, phytotherapy and natural products in pharmacology.</li> </ol> <p><span style="font-weight: 400;">As well as other related lines. All published works are original and their copyright belongs to the Authors.</span></p> <p><strong>Publication language</strong></p> <p>English/Spanish</p> <p><strong>Editing formats</strong></p> <p>The preferred file format for editing in the journal is Microsoft word, which also accepts .pdf files. Files in .jpg, .png, .tiff, and .ppt are accepted for figures. For videos, only .mp4 files are accepted.</p> <p><strong>Declaration</strong></p> <p>The concepts that appear in this publication are the sole responsibility of the authors. The content of the advertising is the responsibility of the advertising companies and institutions. The partial or total reproduction of any article is authorized on the condition of making a bibliographic reference to the <strong>Horizon Interdisciplinary Journal.</strong></p> <div style="background-color: #eeeeee; border: 1px solid #999999; padding: 2%; text-align: center;"> <p>Open reception of articles for our April-June 2023 issue</p> <ol> <li style="text-align: left;">First, check if your manuscript meets all the requirements specified in the <a href="">Submission Preparation Checklist</a></li> <li style="text-align: left;">If your manuscript meets all the requirements, please register <a href="">here</a>, log in and send it to us <a href="">here</a></li> <li style="text-align: left;">Please read all the <a href="">refereeing steps</a> you have to go through to get to the home stretch</li> </ol> <p style="text-align: left;">The Journal accepts Pre-Prints!</p> </div> <p>This work is licensed under a <a href="">Creative Commons Attribution 4.0 International License</a></p> Medical-surgical and sociodemographic aspects in patients with gastroschisis in a Third Level Hospital in Mexico during the period 2018-2022. 2024-05-21T19:44:11+00:00 Guillermo Yanowsky Reyes [email protected] Elvia Ximena Rodriguez Fausto [email protected] Zacnicté Viridiana Corona-Guzmán [email protected] Denisse Estefanía Alfaro-Castellanos [email protected] Franklin Daniel Norori-Escobar [email protected] Arely Jaqueline Pérez Padilla [email protected] Nidia Raquel Álvares-Rosales [email protected] Laura Olivia Montaño-Ángeles [email protected] Carlos Oswaldo Yanowsky-González [email protected] <p><strong>Abstract: Introduction:</strong> Gastroschisis is a birth defect in which a hole in the abdominal wall (Belly) lateral to the umbilicus allows the infant's intestines to be exposed, in addition to other organs such as the stomach and liver. <strong>Objective:</strong> To obtain information on the medical-surgical approach to this congenital anomaly, identify aspects of probable risk in the demographic areas where the pregnant women reside, pathological and non-pathological personal history of the patients' mothers, newborns diagnosed with gastroschisis attended from January 2018 to January 2022 and drug addictions used in the perinatal period of the pregnant women. <strong>Method:</strong> descriptive, retrospective, retrospective, cross-sectional, observational, epidemiological cohort study. An analysis of the clinical records of the Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde of patients with a diagnosis of gastroschisis attended in January 2018 to January 2022 was performed. The data were collected in Microsoft Excel and SPSS 22 software. They were subsequently interpreted and analyzed by means of measures of central tendency and association. <strong>Results:</strong> A sample size of 48 patients was analyzed revealing that the prevalence of gastroschisis in the Antiguo Hospital Civil Fray Antonio Alcalde from 2018 to 2022 was 0.0089%. In addition, 83% success rate was observed in the treatment of patients with gastroschisis in pediatric surgery, with higher prevalence in male neonates (M=55.3%, F=22%), among others. A positive association was found with gastroschisis and exposure to environmental pollutants (OR=1.67), teenage mothers (OR=2) and ORH+ blood group (OR=1.29). The risks by demographic area according to their exposure and locality, 50% exposure to insecticides and 17% to polluting industries. The diagnosis of this malformation was made in 47% in the second trimester, 28% in the first trimester and 23% in the third trimester. Within the personal pathological and non-pathological history of the parents, no pathology of importance was identified. Surgical management was 59.2% with deferred closure and 40% with primary closure, medical management was for 100% of the patients and 16 of them required mechanical ventilation. <strong>Conclusion:</strong> According to the results obtained, the main positive relationship for presenting gastroschisis was the presence of a teenage mother and exposure to environmental pollutants in the studied sample.</p> <p style="font-weight: 400;"><strong>Keywords: </strong>Gastroschisis, medical-surgical approach, risk factors, pregnancy, complications, demographics, teenage mother.</p> 2024-05-13T00:00:00+00:00 Copyright (c) 2024 Zacnicté Corona, Elvia, Guillermo, Franklin Daniel Norori Escobar , Denisse , Nidia, Laura Olivia, Carlos Pediatric testicular tumors: 10 years of clinical approach at the Antiguo Hospital Civil de Guadalajara. 2024-03-05T03:28:26+00:00 José Antonio Gutiérrez-Ureña [email protected] Guillerno Yanowsky Reyes [email protected] Andrea Paola Ramos Mora [email protected] Zacnicté Corona [email protected] Carlos Guillermo Abascal Medina [email protected] Laura Olivia Montaño Ángeles [email protected] Julio Edgardo Flores Revilla [email protected] Jesús Antonio Aguilar Mata [email protected] <p><strong>Abstract. - Introduction: </strong>In recent decades, the prevalence of testicular cancer has increased. The prevalence of testicular cancer in children under 19 years of age worldwide represents the sixth position in terms of frequency. The estimated prevalence is 0.3-3.1, incidence 0.17-1.4 and mortality 0.02-0.1 per 100,000. Considering the increase in the prevalence of testicular cancer, we conducted this study with the intention of knowing the clinical characteristics, the diagnostic and therapeutic approach, as well as the incidence and mortality in our environment. <strong>Methods: </strong>A case series of pediatric patients attended from January 1, 2013 to January 1, 2023 at the Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde was carried out. Age, risk factors, clinical presentation, tumor markers (BHCG, AFP, LDH), imaging studies, therapeutic management, tumor size and histopathological study were reviewed. The data was collected by reviewing clinical records; these data were downloaded into the Office Excel program and transferred to SPSS version 25.<strong> Results: </strong>We analyzed the records of 11 pediatric patients who met the inclusion criteria, 4 patients had a testicular tumor and 7 patients had a paratesticular tumor, estimating an incidence of 0.15/100 000. The mean for age at diagnosis was 14 years with a deviation of 8 with respect to the mean, only 2 patients (18.18%) presented cryptorchidism as a risk factor, all patients presented increased testicular size at diagnosis, tumor markers were positive in 41.6% of the cases in which it was measured. Ultrasound was performed in all cases, the mean size of the masses was 3 cm, 1 patient presented benign histology, while 3 patients presented positivity to malignancy. Five orchiectomies were performed, one lumpectomy and five are still under follow-up and surveillance.<strong> Conclusion: </strong>testicular and paratesticular tumors are infrequent in pediatric age, nevertheless, understanding them is of great importance in order to make an early diagnosis and offer an individualized therapeutic approach, considering limiting radical orchiectomy to cases in which malignancy is suspected.</p> <p><span lang="EN-US"> </span></p> 2024-03-01T00:00:00+00:00 Copyright (c) 2024 José Antonio Gutiérrez-Ureña, Guillerno Yanowsky Reyes, Andrea Paola Ramos Mora, Zacnicté Corona, Carlos Guillermo Abascal Medina, Laura Olivia Montaño Ángeles, Julio Edgardo Flores Revilla, Jesús Antonio Aguilar Mata